The risk for women is as high as or higher than that in men. The wide QRS complexes follow some of the pacing spikes, and show varying degrees of QRS widening due to intramyocardial aberrancy. However, the mortality risk in isolated RBBB group was only significantly increased in women but not in men.ĬONCLUSION: A wide spatial QRS/T angle in BBB is associated with increased risk for CHD and all-cause mortality over and above the predictive value for BBB alone. In the pooled ICVD/LBBB group, the risk for CHD death was increased 15.9-fold in women and 6.04 fold in men, and for all-cause deaths 3.01-fold in women and 1.84-fold in men. Using the No-BBB with QRS/T angle below median value as gender-specific reference groups, the mortality risk increase was significant for both women and men with No-BBB and QRS/T angle above the median value. During a median 22-year follow-up, 4767 deaths occurred, 728 of them CHD deaths. Only 5 of 12 analyzed criteria had a specificity > or 0.
Sex stratified Cox regression models were used to compute hazard ratios (HRs) with 95% confidence intervals (CIs) for coronary heart disease (CHD) and all-cause mortality for wide spatial QRS/T angle with and without BBB including right BBB (RBBB), left BBB (LBBB) and indetermined-type ventricular conduction defect (IVCD) and RBBB combined with left anterior fascicular block. Methods and results: We analyzed prospectively the specificity of the QRS morphological criteria previously described in ECGs during sinus rhythm of 232 patients with IVCD. METHODS AND RESULTS: Total 15,408 participants (mean age 54 years, 55.2% women, 26.9% blacks, 2.8% with BBB) were from the Arteriosclerosis Risk in Communities Study. This study evaluated the prognostic value of QRS/T angle for mortality in the presence and absence of BBB. Zhang Z-M, Rautaharju PM, Prineas RJ, Whitsel EA, Tereshchenko LĪge Distribution, Bundle-Branch Block, Comorbidity, Coronary Artery Disease, Diagnosis, Computer-Assisted, Electrocardiography, Female, Humans, Incidence, Male, Middle Aged, North Carolina, Prognosis, Reproducibility of Results, Risk Factors, Sensitivity and Specificity, Sex Distribution, Survival AnalysisīACKGROUND: Repolarization abnormality in bundle branch blocks (BBB) is traditionally ignored. A wide QRS/T angle in bundle branch blocks is associated with increased risk for coronary heart disease and all-cause mortality in the Atherosclerosis Risk in Communities (ARIC) Study.